Beatriz Orozco Monroy
DNA must be spatially segregated in a synthetic cell after its replication to ensure that, upon cell division, each daughter cell contains enough copies of it. The cytoskeleton is a crucial player in this process as it is composed of protein filaments that can elongate, shrink, and treadmill to pull the genetic material. Using bacteria cytoskeleton proteins that can be cell-free expressed, in this project, we aim to construct a hybrid DNA segregation system that can be encapsulated in liposomes and can be externally controlled, for instance, using light-induced dimers.